PNC-27 5mg
PNC-27 is a chimeric peptide combining the p53 protein HDM-2-binding domain with a cell-penetrating sequence. Research demonstrates selective cytotoxicity against cancer cell lines that overexpress HDM-2 while sparing normal cells. It induces membranolysis specifically in transformed cells through HDM-2 interaction at the cell membrane.
Sequence
Chimeric peptide: p53 HDM-2 binding domain + membrane-penetrating sequence
Market avg: $64.99 — save 42%
Volume pricing
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Certificate of Analysis
Independently verified by Janoshik Analytical
Test ID
JAN-PNC27-2026-001
Purity
96.8%
Method
HPLC-MS
Batch
PNC27-2026-01A
Test Date
February 1, 2026
Identity
Confirmed
Storage Requirements
Lyophilized
-20°C, protect from light
Reconstituted
2-8°C, use within 7 days
Research peptide targeting HDM-2. Store frozen.
Published Research
1 peer-reviewed studies
PNC-27, a chimeric p53-penetratin peptide, is selectively cytotoxic to cancer cells
Kanovsky M, Raffo A, Drew L, et al. — Anti-Cancer Drugs, 2003
Initial characterization of PNC-27 selective anticancer activity via HDM-2 targeting.
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Research use only. All products are sold strictly for in-vitro research purposes only. Not for human consumption. Information provided references published research literature. No medical claims are made or implied.